Studies on imidocarb dihydrochloride in experimental Babesia bigemina infection in calves.
نویسنده
چکیده
Four chemotherapeutic trials in Iran with the babesicide 3,3-bis(2-imidazoline-2-yl) carbanilide dihydrochloride (Imidocarb dihydrochloride) are reported. Subcutaneous administration at a dose of l mg/kg proved highly effective in controlling experimental infection with a local virulent strain of Babesia bigemina in calves. While treated calves were apparently sterilized of the infection, they subsequently (100 days) were resistant to clinical re-infection despite the development-of a low parasitaemia.
منابع مشابه
Studies on imidocarb dihydrochloride in experimental Babesia ovis infection in splenectomized lambs
متن کامل
Chemoprophylaxis (Imidocarb) against Babesia bigemina and Babesia argentina infections.
incoordination, and prostration. Signs of toxicosis were The cht:irprophylactic effects of imidocarb (3,3'milder with intramuscular or subcutaneous injections bis-'2-imidazolin-2-yl)-carbanilide dihydrochloride) of imidocarb. aga.nst bovine babesiasis were evaluated in 29 calves. T.',e compound had prophylactic and therapeutic prop '-jties in calves artificially and naturally infected with Bab...
متن کاملThe retention of Babesia bigemina infection by Boophilus decoloratus exposed to imidocarb dipropionate during engorgement.
Babesia bigemina was retained in the vector Boophilus decoloratus for a complete generation despite the use of the babesicide, imidocarp dipropionate, to prevent reinfection. This drug did not sterilize ticks of the B. bigemina infection as has been suggested for B. bovis.
متن کاملPCR-based detection of Babesia bovis and Babesia bigemina in their natural host Boophilus microplus and cattle.
PCR and nested-PCR methods were used to assess the frequency of Babesia bovis and Babesia bigemina infection in Boophilus microplus engorged females and eggs and in cattle reared in an area with endemic babesiosis. Blood and the engorged female ticks were from 27 naturally infested calves and 25 crossbred cows. The frequency of both Babesia species was similar in calves and cows (P>0.05). Babes...
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ورودعنوان ژورنال:
- The British veterinary journal
دوره 131 6 شماره
صفحات -
تاریخ انتشار 1975